5K8W: Crystal structure of mouse CARM1 in complex with inhibitor U2

PDB ID: 5K8WDownload
MMDB ID: 151869
PDB Deposition Date: 2016/5/31
Updated in MMDB: 2018/06
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5K8W: tetrameric; determined by author and by software (PISA)
Molecular Components in 5K8W
Label Count Molecule
Proteins (4 molecules)
4
Histone-arginine Methyltransferase Carm1
(Gene symbol: Carm1)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
4
9-(7-{[amino(iminio)methyl]amino}-5,6,7-trideoxy-beta-D-ribo-heptofuranosyl)-9H-purin-6-amine9-(7-{[amino(iminio)methyl]amino}-5,6,7-trideoxy-beta-D-ribo-heptofuranosyl)-9H-purin-6-amine
2
6
1,2-DIMETHOXYETHANE1,2-DIMETHOXYETHANE
3
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
5
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303