5K4L: Crystal structure of KDM5A in complex with a naphthyridone inhibitor

PDB ID: 5K4LDownload
MMDB ID: 142171
PDB Deposition Date: 2016/5/20
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.179  Å
Source Organism:
Similar Structures:
Biological Unit for 5K4L: dimeric; determined by author
Molecular Components in 5K4L
Label Count Molecule
Proteins (2 molecules)
2
Lysine-specific Demethylase 5A
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
NICKEL (II) IONNICKEL (II) ION
2
4
ZINC IONZINC ION
3
2
~{N}-ethyl-4-oxidanyl-2-oxidanylidene-1~{H}-1,7-naphthyridine-3-carboxamide~{N}-ethyl-4-oxidanyl-2-oxidanylidene-1~{H}-1,7-naphthyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303