5K3Y: Crystal structure of AuroraB/INCENP in complex with BI 811283

PDB ID: 5K3YDownload
MMDB ID: 142486
PDB Deposition Date: 2016/5/20
Updated in MMDB: 2022/12
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5K3Y: dimeric; determined by software (PISA)
Molecular Components in 5K3Y
Label Count Molecule
Proteins (2 molecules)
1
Aurora Kinase B-A
(Gene symbol: aurkb.L)
Molecule annotation
1
Inner Centromere Protein a
(Gene symbol: incenp.L)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-methyl-N-(1-methylpiperidin-4-yl)-4-{[4-({(1R,2S)-2-[(propan-2-yl)carbamoyl]cyclopentyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzamide (Link to PubChem not yet available)N-methyl-N-(1-methylpiperidin-4-yl)-4-{[4-({(1R,2S)-2-[(propan-2-yl)carbamoyl]cyclopentyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303