5K0M: Targeting the PRC2 complex through a novel protein-protein interaction inhibitor of EED

PDB ID: 5K0MDownload
MMDB ID: 146788
PDB Deposition Date: 2016/5/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.83  Å
Source Organism:
Similar Structures:
Biological Unit for 5K0M: monomeric; determined by author and by software (PISA)
Molecular Components in 5K0M
Label Count Molecule
Protein (1 molecule)
1
Polycomb Protein EED
(Gene symbol: EED)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}pyrrolidin-3-amine(3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}pyrrolidin-3-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303