5JVZ: Crystal structure of flurbiprofen bound to S121P murine COX-2 mutant

PDB ID: 5JVZDownload
MMDB ID: 144388
PDB Deposition Date: 2016/5/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.62  Å
Source Organism:
Similar Structures:
Biological Unit for 5JVZ: dimeric; determined by author and by software (PISA)
Molecular Components in 5JVZ
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin G/H Synthase 2
(Gene symbol: Ptgs2)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
2
FLURBIPROFENFLURBIPROFEN
4
2
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
5
2
PROTOPORPHYRIN IX CONTAINING COPROTOPORPHYRIN IX CONTAINING CO
6
4
ACRYLIC ACIDACRYLIC ACID
7
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303