5JNL: Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC54 and manganese

PDB ID: 5JNLDownload
MMDB ID: 142290
PDB Deposition Date: 2016/4/30
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5JNL: dimeric; determined by author and by software (PISA)
Molecular Components in 5JNL
Label Count Molecule
Proteins (2 molecules)
2
1-deoxy-d-xylulose 5-phosphate Reductoisomerase, Apicoplastic
(Gene symbol: PF3D7_1467300)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
2
{(2R)-2-{2-[hydroxy(methyl)amino]-2-oxoethyl}-5-[4-(trifluoromethyl)phenyl]pentyl}phosphonic acid{(2R)-2-{2-[hydroxy(methyl)amino]-2-oxoethyl}-5-[4-(trifluoromethyl)phenyl]pentyl}phosphonic acid
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
4
GLYCEROLGLYCEROL
4
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303