5JLJ: Crystal Structure of KPT8602 in complex with CRM1-Ran-RanBP1

PDB ID: 5JLJDownload
MMDB ID: 140575
PDB Deposition Date: 2016/4/27
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Saccharomyces cerevisiae S288C▼
Similar Structures:
Biological Unit for 5JLJ: trimeric; determined by author and by software (PISA)
Molecular Components in 5JLJ
Label Count Molecule
Proteins (3 molecules)
1
Gtp-binding Nuclear Protein RAN
Molecule annotation
1
Ran-specific Gtpase-activating Protein 1
Molecule annotation
1
Exportin-1
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
5
GLYCEROLGLYCEROL
4
1
CHLORIDE IONCHLORIDE ION
5
1
(2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide(2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303