5JI0: PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid

PDB ID: 5JI0Download
MMDB ID: 150074
PDB Deposition Date: 2016/4/21
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 5JI0: tetrameric; determined by author
Molecular Components in 5JI0
Label Count Molecule
Proteins (4 molecules)
1
Retinoic Acid Receptor Rxr-alpha
(Gene symbol: RXRA)
Molecule annotation
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
2
Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(9cis)-retinoic acid(9cis)-retinoic acid
2
1
2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL)2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303