5JFX: Crystal structure of TrkA in complex with PF-06273340

PDB ID: 5JFXDownload
MMDB ID: 147702
PDB Deposition Date: 2016/4/19
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 5JFX: monomeric; determined by author and by software (PISA)
Molecular Components in 5JFX
Label Count Molecule
Protein (1 molecule)
1
High Affinity Nerve Growth Factor Receptor
(Gene symbol: NTRK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}-2-(5-chloropyridin-2-yl)acetamideN-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}-2-(5-chloropyridin-2-yl)acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303