5JFO: Structure of the M.tuberculosis enoyl-reductase InhA in complex with GSK625

PDB ID: 5JFODownload
MMDB ID: 142147
PDB Deposition Date: 2016/4/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.907  Å
Source Organism:
Similar Structures:
Biological Unit for 5JFO: tetrameric; determined by author and by software (PISA)
Molecular Components in 5JFO
Label Count Molecule
Proteins (4 molecules)
4
Enoyl-[acyl-carrier-protein] Reductase [nadh]
(Gene symbol: inhA)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
4
N-{1-[(2-chloro-6-fluorophenyl)methyl]-1H-pyrazol-3-yl}-5-[(1S)-1-(3-methyl-1H-pyrazol-1-yl)ethyl]-1,3,4-thiadiazol-2-amineN-{1-[(2-chloro-6-fluorophenyl)methyl]-1H-pyrazol-3-yl}-5-[(1S)-1-(3-methyl-1H-pyrazol-1-yl)ethyl]-1,3,4-thiadiazol-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303