5JEB: Crystal structure of EGFR tyrosine kinase domain with novel inhibitor of active state of HER2

PDB ID: 5JEBDownload
MMDB ID: 142836
PDB Deposition Date: 2016/4/18
Updated in MMDB: 2016/11
Experimental Method:
x-ray diffraction
Resolution: 3.298  Å
Source Organism:
Similar Structures:
Biological Unit for 5JEB: monomeric; determined by author and by software (PISA)
Molecular Components in 5JEB
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SULFATE IONSULFATE ION
2
1
3-(furan-2-yl)-N-[5-(furan-2-yl)-2-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine3-(furan-2-yl)-N-[5-(furan-2-yl)-2-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303