5JAS: Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening

PDB ID: 5JASDownload
MMDB ID: 139624
PDB Deposition Date: 2016/4/12
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.06  Å
Source Organism:
Similar Structures:
Biological Unit for 5JAS: monomeric; determined by author and by software (PISA)
Molecular Components in 5JAS
Label Count Molecule
Protein (1 molecule)
1
Platelet-activating Factor Acetylhydrolase
(Gene symbol: PLA2G7)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
N-(2',6-dimethyl[1,1'-biphenyl]-3-yl)-1,3-thiazol-2-amineN-(2',6-dimethyl[1,1'-biphenyl]-3-yl)-1,3-thiazol-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303