5J5S: Src kinase in complex with a sulfonamide inhibitor

PDB ID: 5J5SDownload
MMDB ID: 139785
PDB Deposition Date: 2016/4/3
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.153  Å
Source Organism:
Similar Structures:
Biological Unit for 5J5S: monomeric; determined by author and by software (PISA)
Molecular Components in 5J5S
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Tyrosine-protein Kinase SRC
(Gene symbol: SRC)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{4-[8-amino-3-(propan-2-yl)imidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl}-N'-[3-(trifluoromethyl)phenyl]ureaN-{4-[8-amino-3-(propan-2-yl)imidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl}-N'-[3-(trifluoromethyl)phenyl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303