5J42: Crystal structure of m2hTDP2-CAT in complex with a small molecule inhibitor

PDB ID: 5J42Download
MMDB ID: 139014
PDB Deposition Date: 2016/3/31
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 5J42: monomeric; determined by author
Molecular Components in 5J42
Label Count Molecule
Protein (1 molecule)
1
Tyrosyl-dna Phosphodiesterase 2
(Gene symbol: Tdp2)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
10-(4-hydroxyphenyl)-2,4-dioxo-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile10-(4-hydroxyphenyl)-2,4-dioxo-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile
2
5
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
3
1
GLYCEROLGLYCEROL
4
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303