5J3Z: Crystal structure of m2hTDP2-CAT in complex with a small molecule inhibitor

PDB ID: 5J3ZDownload
MMDB ID: 139013
PDB Deposition Date: 2016/3/31
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5J3Z: monomeric; determined by author
Molecular Components in 5J3Z
Label Count Molecule
Protein (1 molecule)
1
Tyrosyl-dna Phosphodiesterase 2
(Gene symbol: Tdp2)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
2
2,4-dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile2,4-dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
GLYCEROLGLYCEROL
4
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303