5J2M: HIV-1 reverse transcriptase in complex with DNA and EFdA-triphosphate, a translocation-defective RT inhibitor

PDB ID: 5J2MDownload
MMDB ID: 141561
PDB Deposition Date: 2016/3/29
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.432  Å
Source Organism:
HIV-1 M:B_HXB2R▼
Similar Structures:
Biological Unit for 5J2M: tetrameric; determined by author and by software (PISA)
Molecular Components in 5J2M
Label Count Molecule
Proteins (2 molecules)
1
Hiv-1 Reverse Transcriptase P51 Subunit
Molecule annotation
1
Hiv-1 Reverse Transcriptase P51 Subunit
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*ap*cp*ap*gp*tp*cp*cp*cp*tp*gp*tp*tp*cp*gp*gp*(mrg)p*cp*gp*cp*cp*g)-3')
Molecule annotation
1
DNA (27-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
3
MAGNESIUM IONMAGNESIUM ION
2
1
2'-deoxy-4'-ethynyl-2-fluoroadenosine 5'-(tetrahydrogen triphosphate)2'-deoxy-4'-ethynyl-2-fluoroadenosine 5'-(tetrahydrogen triphosphate)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303