5IZ0: RORgamma in complex with agonist BIO592 and Coactivator EBI96

PDB ID: 5IZ0Download
MMDB ID: 140131
PDB Deposition Date: 2016/3/24
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.635  Å
Source Organism:
Similar Structures:
Biological Unit for 5IZ0: dimeric; determined by author and by software (PISA)
Molecular Components in 5IZ0
Label Count Molecule
Proteins (2 molecules)
1
Nuclear Receptor Ror-gamma
(Gene symbol: RORC)
Molecule annotation
1
Glu-phe-pro-tyr-leu-leu-ser-leu-leu-gly-glu-val-ser-pro-gln
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
N-(4-ethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-3,4-dimethyl-N-(2,2,2-trifluoroethyl)benzene-1-sulfonamideN-(4-ethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-3,4-dimethyl-N-(2,2,2-trifluoroethyl)benzene-1-sulfonamide
2
8
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303