5IWI: 1.98A structure of GSK945237 with S.aureus DNA gyrase and singly nicked DNA

PDB ID: 5IWIDownload
MMDB ID: 139593
PDB Deposition Date: 2016/3/22
Updated in MMDB: 2016/07
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Staphylococcus aureus subsp. aureus N315▼
Similar Structures:
Biological Unit for 5IWI: heptameric; determined by author and by software (PISA)
Molecular Components in 5IWI
Label Count Molecule
Proteins (4 molecules)
2
DNA Gyrase Subunit B,dna Gyrase Subunit B
Molecule annotation
2
DNA Gyrase Subunit a
Molecule annotation
Nucleotides(3 molecules)
1
DNA (5'-d(*ap*gp*cp*cp*gp*tp*ap*gp*gp*tp*ap*cp*ap*cp*cp*gp*cp*ap*cp*a)-3')
Molecule annotation
1
DNA (5'-d(*tp*gp*tp*gp*cp*gp*gp*t*gp*tp*ap*cp*cp*tp*ap*cp*gp*gp*cp*t)-3')
Molecule annotation
1
DNA (5'-d(*tp*gp*tp*gp*cp*gp*gp*t*gp*tp*ap*cp*cp*tp*ap*cp*gp*gp*cp*t)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
3
MANGANESE (II) IONMANGANESE (II) ION
2
10
GLYCEROLGLYCEROL
3
1
CHLORIDE IONCHLORIDE ION
4
1
(1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one(1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303