5IVJ: Linked KDM5A Jmj Domain Bound to the Inhibitor N11 [3-({1-[2-(4,4-difluoropiperidin-1-yl)ethyl]-5-fluoro-1H-indazol-3-yl}amino)pyridine-4-carboxylic acid]

PDB ID: 5IVJDownload
MMDB ID: 141374
PDB Deposition Date: 2016/3/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.569  Å
Source Organism:
Similar Structures:
Biological Unit for 5IVJ: monomeric; determined by author
Molecular Components in 5IVJ
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5A
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
3-({1-[2-(4,4-difluoropiperidin-1-yl)ethyl]-5-fluoro-1H-indazol-3-yl}amino)pyridine-4-carboxylic acid3-({1-[2-(4,4-difluoropiperidin-1-yl)ethyl]-5-fluoro-1H-indazol-3-yl}amino)pyridine-4-carboxylic acid
2
1
MANGANESE (II) IONMANGANESE (II) ION
3
1
GLYCEROLGLYCEROL
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303