5IVE: Linked KDM5A Jmj Domain Bound to the Inhibitor N8 ( 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile)

PDB ID: 5IVEDownload
MMDB ID: 141372
PDB Deposition Date: 2016/3/20
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.783  Å
Source Organism:
Similar Structures:
Biological Unit for 5IVE: monomeric; determined by author
Molecular Components in 5IVE
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5A
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile
2
1
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303