5ISL: Linked KDM5A Jmj Domain Bound to the Inhibitor C49 (2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid)

PDB ID: 5ISLDownload
MMDB ID: 141368
PDB Deposition Date: 2016/3/15
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.694  Å
Source Organism:
Similar Structures:
Biological Unit for 5ISL: monomeric; determined by author
Molecular Components in 5ISL
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5A
(Gene symbol: KDM5A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid
2
1
MANGANESE (II) IONMANGANESE (II) ION
3
1
GLYCEROLGLYCEROL
4
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303