5ISH: Crystal structure of mouse CARM1 in complex with inhibitor SA0765

PDB ID: 5ISHDownload
MMDB ID: 148075
PDB Deposition Date: 2016/3/15
Updated in MMDB: 2018/06
Experimental Method:
x-ray diffraction
Resolution: 2.152  Å
Source Organism:
Similar Structures:
Biological Unit for 5ISH: tetrameric; determined by software (PISA)
Molecular Components in 5ISH
Label Count Molecule
Proteins (4 molecules)
4
Histone-arginine Methyltransferase Carm1
(Gene symbol: Carm1)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
4
5'-{1-[(3S)-3-amino-3-carboxypropyl]aziridin-1-ium-1-yl}-5'-deoxyadenosine5'-{1-[(3S)-3-amino-3-carboxypropyl]aziridin-1-ium-1-yl}-5'-deoxyadenosine
2
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
4
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
6
1,2-DIMETHOXYETHANE1,2-DIMETHOXYETHANE
5
1
1-METHOXY-2-(2-METHOXYETHOXY)ETHANE1-METHOXY-2-(2-METHOXYETHOXY)ETHANE
6
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303