5IRX: Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc

PDB ID: 5IRXDownload
MMDB ID: 139589
PDB Deposition Date: 2016/3/14
Updated in MMDB: 2019/12
Experimental Method:
electron microscopy
Resolution: 2.95  Å
Source Organism:
Cyriopagopus schmidti▼
Similar Structures:
Biological Unit for 5IRX: hexameric; determined by author
Molecular Components in 5IRX
Label Count Molecule
Proteins (6 molecules)
4
Transient Receptor Potential Cation Channel Subfamily V Member 1
Molecule annotation
2
Tau-theraphotoxin-hs1a
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
4
(4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium(4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium
2
8
(2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate(2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate
3
4
resiniferatoxinresiniferatoxin
4
4
(2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate(2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303