5IJ8: Structure of the primary oncogenic mutant Y641N Hs/AcPRC2 in complex with a pyridone inhibitor

PDB ID: 5IJ8Download
MMDB ID: 138990
PDB Deposition Date: 2016/3/1
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.99  Å
Source Organism:
Similar Structures:
Biological Unit for 5IJ8: trimeric; determined by author and by software (PISA)
Molecular Components in 5IJ8
Label Count Molecule
Proteins (3 molecules)
1
Enhancer of Zeste Homolog 2 (Ezh2),histone-lysine N-methyltransferase Ezh2(Gene symbol: EZH2)
Molecule annotation
1
Polycomb Protein EED(Gene symbol: EED)
Molecule annotation
1
Polycomb Protein Suz12(Gene symbol: SUZ12)
Molecule annotation
Chemicals (8 molecules)
1
1
2
7
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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