5IG6: Ultra-high resolution crystal structure of second bromodomain of BRD2 in complex with inhibitor 6B3

PDB ID: 5IG6Download
MMDB ID: 140292
PDB Deposition Date: 2016/2/27
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 0.91  Å
Source Organism:
Similar Structures:
Biological Unit for 5IG6: monomeric; determined by author and by software (PISA)
Molecular Components in 5IG6
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 2
(Gene symbol: BRD2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
GLYCEROLGLYCEROL
3
1
2'-[(6-oxo-5,6-dihydrophenanthridin-3-yl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid2'-[(6-oxo-5,6-dihydrophenanthridin-3-yl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303