5IFS: Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death

PDB ID: 5IFSDownload
MMDB ID: 144341
PDB Deposition Date: 2016/2/26
Updated in MMDB: 2016/11
Experimental Method:
x-ray diffraction
Resolution: 2.46  Å
Source Organism:
Similar Structures:
Biological Unit for 5IFS: tetrameric; determined by author and by software (PISA)
Molecular Components in 5IFS
Label Count Molecule
Proteins (4 molecules)
2
Tether Containing UBX Domain for Glut4
(Gene symbol: ASPSCR1)
Molecule annotation
2
Transitional Endoplasmic Reticulum Atpase
(Gene symbol: VCP)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
SULFATE IONSULFATE ION
4
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303