5IAW: Novel natural FXR modulator with a unique binding mode

PDB ID: 5IAWDownload
MMDB ID: 147847
PDB Deposition Date: 2016/2/22
Updated in MMDB: 2017/05
Experimental Method:
x-ray diffraction
Resolution: 2.58  Å
Source Organism:
Similar Structures:
Biological Unit for 5IAW: dimeric; determined by author and by software (PISA)
Molecular Components in 5IAW
Label Count Molecule
Proteins (2 molecules)
1
Bile Acid Receptor
(Gene symbol: NR1H4)
Molecule annotation
1
Peptide From Nuclear Receptor Coactivator 2
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 4-hydroxybenzoate(1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 4-hydroxybenzoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303