5IA4: Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with foretinib (XL880)

PDB ID: 5IA4Download
MMDB ID: 144721
PDB Deposition Date: 2016/2/21
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 1.797  Å
Source Organism:
Similar Structures:
Biological Unit for 5IA4: monomeric; determined by author and by software (PISA)
Molecular Components in 5IA4
Label Count Molecule
Protein (1 molecule)
1
Ephrin Type-a Receptor 2
(Gene symbol: EPHA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideN-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303