5I94: Crystal structure of human glutaminase C in complex with the inhibitor UPGL-00019

PDB ID: 5I94Download
MMDB ID: 139192
PDB Deposition Date: 2016/2/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.983  Å
Source Organism:
Similar Structures:
Biological Unit for 5I94: tetrameric; determined by author and by software (PISA)
Molecular Components in 5I94
Label Count Molecule
Proteins (4 molecules)
4
Glutaminase Kidney Isoform, Mitochondrial
(Gene symbol: GLS)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303