5I5K: Structure of complement C5 in complex with eculizumab

PDB ID: 5I5KDownload
MMDB ID: 137561
PDB Deposition Date: 2016/2/15
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 4.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5I5K: trimeric; determined by author and by software (PISA)
Molecular Components in 5I5K
Label Count Molecule
Proteins (3 molecules)
1
Complement C5
(Gene symbol: C5)
Molecule annotation
1
Eculizumab Heavy Chain (Variable Domain)
Molecule annotation
1
Eculizumab Light Chain (Variable Domain)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303