5I4U: The crystal structure of PI3Kdelta with compound 34

PDB ID: 5I4UDownload
MMDB ID: 147475
PDB Deposition Date: 2016/2/12
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.372  Å
Source Organism:
Similar Structures:
Biological Unit for 5I4U: monomeric; determined by author
Molecular Components in 5I4U
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Delta Isoform
(Gene symbol: Pik3cd)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2,4-diamino-6-{[(1S)-1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl]amino}pyrimidine-5-carbonitrile2,4-diamino-6-{[(1S)-1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl]amino}pyrimidine-5-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303