5I2K: Structure of the human GluN1/GluN2A LBD in complex with 7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide (compound 19)

PDB ID: 5I2KDownload
MMDB ID: 137557
PDB Deposition Date: 2016/2/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.86  Å
Source Organism:
Similar Structures:
Biological Unit for 5I2K: dimeric; determined by author and by software (PISA)
Molecular Components in 5I2K
Label Count Molecule
Proteins (2 molecules)
1
Glutamate Receptor Ionotropic, Nmda 2A
(Gene symbol: GRIN2A)
Molecule annotation
1
Glutamate Receptor Ionotropic, Nmda 1
(Gene symbol: GRIN1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GLUTAMIC ACIDGLUTAMIC ACID
2
1
GLYCINEGLYCINE
3
1
7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303