5HYN: Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide

PDB ID: 5HYNDownload
MMDB ID: 139190
PDB Deposition Date: 2016/2/1
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5HYN: pentameric; determined by author
Molecular Components in 5HYN
Label Count Molecule
Proteins (5 molecules)
1
Histone-lysine N-methyltransferase Ezh2
(Gene symbol: EZH2)
Molecule annotation
1
Polycomb Protein EED
(Gene symbol: EED)
Molecule annotation
1
Polycomb Protein Suz12
(Gene symbol: SUZ12)
Molecule annotation
1
H3k27m
Molecule annotation
1
Jarid2 K116me3
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
8
ZINC IONZINC ION
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303