5HY8: Glycation restrains allosteric transition in hemoglobin: The molecular basis of oxidative stress under hyperglycemic conditions in diabetes

PDB ID: 5HY8Download
MMDB ID: 146969
PDB Deposition Date: 2016/2/1
Updated in MMDB: 2025/12
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5HY8: tetrameric; determined by author
Molecular Components in 5HY8
Label Count Molecule
Proteins (4 molecules)
2
Hemoglobin Subunit Alpha
(Gene symbol: HBA1)
Molecule annotation
2
Hemoglobin Subunit Beta
(Gene symbol: HBB)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
OXYGEN MOLECULEOXYGEN MOLECULE
3
1
beta-D-fructofuranosebeta-D-fructofuranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303