5HVT: Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2)

PDB ID: 5HVTDownload
MMDB ID: 140536
PDB Deposition Date: 2016/1/28
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 5HVT: trimeric; determined by author and by software (PISA)
Molecular Components in 5HVT
Label Count Molecule
Proteins (3 molecules)
3
Macrophage Migration Inhibitory Factor
(Gene symbol: MIF)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
6
SULFATE IONSULFATE ION
2
3
7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one
3
3
GLYCEROLGLYCEROL
4
3
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303