5HU9: Crystal structure of ABL1 in complex with CHMFL-074

PDB ID: 5HU9Download
MMDB ID: 141146
PDB Deposition Date: 2016/1/27
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 1.529  Å
Source Organism:
Similar Structures:
Biological Unit for 5HU9: monomeric; determined by author and by software (PISA)
Molecular Components in 5HU9
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Abl1
(Gene symbol: ABL1)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
2
4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide
2
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303