5HTZ: Bace1 In Complex With (s)-5-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3- Yl)thiophen-2-yl)-2,5-dimethyl-1,2,4-thiadiazinan-3-iminium 1,1- Dioxide

PDB ID: 5HTZDownload
MMDB ID: 144704
PDB Deposition Date: 2016/1/27
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5HTZ: monomeric; determined by author and by software (PISA)
Molecular Components in 5HTZ
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3e,5s)-5-{3-Chloro-5-[5-(Prop-1-Yn-1-Yl)pyridin-3-Yl]thiophen-2-Yl}-2,5-Dimethyl-1,2,4-Thiadiazinan-3-Imine 1,1-Dioxide(3e,5s)-5-{3-Chloro-5-[5-(Prop-1-Yn-1-Yl)pyridin-3-Yl]thiophen-2-Yl}-2,5-Dimethyl-1,2,4-Thiadiazinan-3-Imine 1,1-Dioxide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303