5HS3: Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol

PDB ID: 5HS3Download
MMDB ID: 136805
PDB Deposition Date: 2016/1/25
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3.103  Å
Source Organism:
Similar Structures:
Biological Unit for 5HS3: dimeric; determined by author
Molecular Components in 5HS3
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: TYMS)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
1
3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303