5HRS: HIV Integrase Catalytic Domain containing F185K + A124N + T125A mutations complexed with GSK0002

PDB ID: 5HRSDownload
MMDB ID: 145602
PDB Deposition Date: 2016/1/24
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 1.86  Å
Source Organism:
Similar Structures:
Biological Unit for 5HRS: dimeric; determined by author and by software (PISA)
Molecular Components in 5HRS
Label Count Molecule
Proteins (2 molecules)
2
Integrase
(Gene symbol: gag-pol)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
CACODYLATE IONCACODYLATE ION
2
4
SULFATE IONSULFATE ION
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
2
(2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid(2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303