5HQ0: Ternary complex of human proteins CDK1, Cyclin B and CKS2, bound to an inhibitor

PDB ID: 5HQ0Download
MMDB ID: 137078
PDB Deposition Date: 2016/1/21
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5HQ0: trimeric; determined by author and by software (PISA)
Molecular Components in 5HQ0
Label Count Molecule
Proteins (3 molecules)
1
Cyclin-dependent Kinase 1
(Gene symbol: CDK1)
Molecule annotation
1
G2/mitotic-specific Cyclin-b1
(Gene symbol: CCNB1)
Molecule annotation
1
Cyclin-dependent Kinases Regulatory Subunit 2
(Gene symbol: CKS2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
{[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide{[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303