5HP1: STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE In COMPLEX WITH A DNA aptamer and FOSCARNET, a Pyrophosphate analog

PDB ID: 5HP1Download
MMDB ID: 139757
PDB Deposition Date: 2016/1/19
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 5HP1: trimeric; determined by author and by software (PISA)
Molecular Components in 5HP1
Label Count Molecule
Proteins (2 molecules)
1
Hiv-1 Reverse Transcriptase P66 Subunit
Molecule annotation
1
Hiv-1 Reverse Transcriptase P51 Subunit
Molecule annotation
Nucleotide(1 molecule)
1
DNA (38-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
2
alpha-D-glucopyranosealpha-D-glucopyranose
2
2
beta-D-fructofuranosebeta-D-fructofuranose
3
5
MAGNESIUM IONMAGNESIUM ION
4
1
PHOSPHONOFORMIC ACIDPHOSPHONOFORMIC ACID
5
1
SULFATE IONSULFATE ION
6
2
GLYCEROLGLYCEROL
7
1
3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303