5HO7: DISCOVERY OF NOVEL 7-AZAINDOLES AS PDK1 INHIBITORS

PDB ID: 5HO7Download
MMDB ID: 139928
PDB Deposition Date: 2016/1/19
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 5HO7: monomeric; determined by author and by software (PISA)
Molecular Components in 5HO7
Label Count Molecule
Protein (1 molecule)
1
3-phosphoinositide-dependent Protein Kinase 1
(Gene symbol: PDPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
5-amino-3-(methylsulfanyl)-1H-pyrazole-1,4-dicarboxamide5-amino-3-(methylsulfanyl)-1H-pyrazole-1,4-dicarboxamide
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303