5HMK: HDM2 in complex with a 3,3-Disubstituted Piperidine

PDB ID: 5HMKDownload
MMDB ID: 138186
PDB Deposition Date: 2016/1/16
Updated in MMDB: 2016/04
Experimental Method:
x-ray diffraction
Resolution: 2.17  Å
Source Organism:
Similar Structures:
Biological Unit for 5HMK: monomeric; determined by author and by software (PISA)
Molecular Components in 5HMK
Label Count Molecule
Protein (1 molecule)
1
E3 Ubiquitin-protein Ligase Mdm2
(Gene symbol: MDM2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
{4-[2-(2-hydroxyethoxy)phenyl]piperazin-1-yl}[(2R,3S)-2-propyl-3-[4-(trifluoromethyl)phenoxy]-1-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}piperidin-3-yl]methanone{4-[2-(2-hydroxyethoxy)phenyl]piperazin-1-yl}[(2R,3S)-2-propyl-3-[4-(trifluoromethyl)phenoxy]-1-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}piperidin-3-yl]methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303