5HM0: Crystal structure of the first bromodomain of human BRD4 bound to benzoisoxazoloazepine 3

PDB ID: 5HM0Download
MMDB ID: 136457
PDB Deposition Date: 2016/1/15
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.395  Å
Source Organism:
Similar Structures:
Biological Unit for 5HM0: monomeric; determined by author and by software (PISA)
Molecular Components in 5HM0
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-(4-chlorophenyl)-1-methyl-4H-[1,2]oxazolo[5,4-d][2]benzazepine6-(4-chlorophenyl)-1-methyl-4H-[1,2]oxazolo[5,4-d][2]benzazepine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303