5HIN: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18L compound

PDB ID: 5HINDownload
MMDB ID: 140772
PDB Deposition Date: 2016/1/12
Updated in MMDB: 2016/07
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5HIN: monomeric; determined by author and by software (PISA)
Molecular Components in 5HIN
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase (Quinone), Mitochondrial
(Gene symbol: DHODH)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
2
1
OROTIC ACIDOROTIC ACID
3
5
SULFATE IONSULFATE ION
4
1
methyl (2Z)-(3-{4-[(4-tert-butylphenyl)carbamoyl]phenyl}-4-oxo-1,3-thiazolidin-2-ylidene)(cyano)acetatemethyl (2Z)-(3-{4-[(4-tert-butylphenyl)carbamoyl]phenyl}-4-oxo-1,3-thiazolidin-2-ylidene)(cyano)acetate
5
2
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303