5HIA: Human hypoxanthine-guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((S)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine

PDB ID: 5HIADownload
MMDB ID: 146496
PDB Deposition Date: 2016/1/11
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.773  Å
Source Organism:
Similar Structures:
Biological Unit for 5HIA: tetrameric; determined by author and by software (PISA)
Molecular Components in 5HIA
Label Count Molecule
Proteins (4 molecules)
4
Hypoxanthine-guanine Phosphoribosyltransferase
(Gene symbol: HPRT1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
4
[3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-y l]-3-oxidanylidene-propyl]phosphonic acid[3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-y l]-3-oxidanylidene-propyl]phosphonic acid
2
8
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303