5HI5: Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

PDB ID: 5HI5Download
MMDB ID: 142590
PDB Deposition Date: 2016/1/11
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Homo sapiens
Similar Structures:
Biological Unit for 5HI5: heptameric; determined by author
Molecular Components in 5HI5
Label Count Molecule
Proteins (7 molecules)
2
Interleukin-17a(Gene symbol: IL17A)
Molecule annotation
2
Cat-2000 FAB Heavy Chain
Molecule annotation
2
Cat-2000 Light Chain
Molecule annotation
1
Synthetic Il-17a Inhibitor
Molecule annotation
Chemical (1 molecule)
1
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB
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