5HE4: Bace-1 In Complex With (4ar,7as)-7a-(2,6-difluorophenyl)-6-(5-fluoro- 4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h- Pyrrolo[3,4-d]pyrimidin-2-iminium

PDB ID: 5HE4Download
MMDB ID: 137542
PDB Deposition Date: 2016/1/5
Updated in MMDB: 2016/06
Experimental Method:
x-ray diffraction
Resolution: 1.53  Å
Source Organism:
Similar Structures:
Biological Unit for 5HE4: monomeric; determined by author and by software (PISA)
Molecular Components in 5HE4
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2e,4ar,7as)-7a-(2,6-Difluorophenyl)-6-(5-Fluoro-4-Methoxy-6-Methylpyrimidin-2-Yl)-2-Imino-3-Methyloctahydro-4h-Pyrrolo[3,4-D]pyrimidin-4-One(2e,4ar,7as)-7a-(2,6-Difluorophenyl)-6-(5-Fluoro-4-Methoxy-6-Methylpyrimidin-2-Yl)-2-Imino-3-Methyloctahydro-4h-Pyrrolo[3,4-D]pyrimidin-4-One
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303