5HDX: Bace-1 In Complex With (7ar)-7a-(5-cyanothiophen-2-yl)-6-(4-ethoxy-5- Fluoro-6-methylpyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3, 4-d]pyrimidin-2-iminium

PDB ID: 5HDXDownload
MMDB ID: 137540
PDB Deposition Date: 2016/1/5
Updated in MMDB: 2016/06
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5HDX: monomeric; determined by author and by software (PISA)
Molecular Components in 5HDX
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[(2e,4ar,7ar)-6-(4-Ethoxy-5-Fluoro-6-Methylpyrimidin-2-Yl)-2-Imino-3-Methyl-4-Oxooctahydro-7ah-Pyrrolo[3,4-D]pyrimidin-7a-Yl]thiophene-2-Carbonitrile5-[(2e,4ar,7ar)-6-(4-Ethoxy-5-Fluoro-6-Methylpyrimidin-2-Yl)-2-Imino-3-Methyl-4-Oxooctahydro-7ah-Pyrrolo[3,4-D]pyrimidin-7a-Yl]thiophene-2-Carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303