5HBM: Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase

PDB ID: 5HBMDownload
MMDB ID: 136798
PDB Deposition Date: 2015/12/31
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 3.043  Å
Source Organism:
Similar Structures:
Biological Unit for 5HBM: dimeric; determined by author and by software (PISA)
Molecular Components in 5HBM
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
P51 RT
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE
2
1
(7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid(7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid
3
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303